This is a big part of it for me. No matter how it's done - sequential turbos, single smaller turbo, etc. - it always seems to result in a compromised torque curve with lumpy power delivery. While I'm not a pro driver, and I'm not driving in competitive motorsports, there's still something disconcerting about an on-rush of power that's incongruent to the throttle input, simply because the engine is suddenly getting force-fed... and then at differing amounts within the turbo-engaged part of the power band. It's kind of like "dynamic steering" to me... don't suddenly change the steering ratio while I'm turning!
I suppose, like any other characteristic, these can be mastered, predicted, and work to one's benefit... but I just don't appreciate it..
That said, I'm a sucker for a high-revving engine, so if Lamborghini can really pull off a 10k redline, no less on a turbo car, that'll be something to experience.